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Shen Ling Bai Zhu San is the most commonly cited classical formula for chronic diarrhea due to Spleen Qi Deficiency with Dampness. For IBS-D triggered by stress (Liver-Spleen disharmony), Tong Xie Yao Fang (痛泻要方) is the classical formula. A 2021 network meta-analysis confirmed that Jianpi-Chushi (strengthening Spleen and draining Dampness) therapy significantly improved global IBS symptoms and IBS-SSS scores.
A network meta-analysis of 28 RCTs involving 3,323 IBS patients reported that Chinese herbal medicine (CHM) may help relieve IBS clinical symptoms. However, the evidence quality was rated as low overall, and these findings are preliminary. Specific CHM strategies were reported to show improvement over conventional therapies for global symptoms, abdominal pain, and bloating respectively, but significant limitations exist. This does not establish a treatment recommendation.