Tracking evidences of Coptis chinensis for the treatment of inflammatory bowel disease from pharmacological, pharmacokinetic to clinical studies

2020|Journal of Ethnopharmacology|Yang Y, Vong CT, Zeng S, Gao C, Chen Z, Fu C, Wang S, Zou L, Wang A, Wang Y

Moderate

Study Type

review article

Human / Animal / In Vitro

human

Evidence Snapshot

Traditional Use

Moderate

Human Evidence

Moderate

Research Consistency

Insufficient

Safety Evidence

Insufficient

Abstract

This comprehensive review examined Coptis chinensis (Huang Lian) and berberine for inflammatory bowel disease treatment. Therapeutic effects are exerted through inhibition of oxidative stress, antinociception, protection of intestinal mucosal epithelial barrier, regulation of T helper cells, and antibacterial activity. Berberine is considered the representative bioactive compound, but many other chemical components also show therapeutic potential.

Linked Entities

Related Herbs

(1)

Huang Lian

黄连

Original Source

DOI: 10.1016/j.jep.2020.113573

PubMed ID: 33181286

References

References are being reviewed

Published July 2, 2026Reviewed content

Medical Disclaimer: The information on TCMIO is provided for educational purposes only. It is not intended as medical advice, diagnosis, or treatment.

Always consult a qualified healthcare professional before using any herbal products, starting any new treatment, or making changes to your existing healthcare regimen. Do not stop or modify any prescribed treatment without consulting your healthcare provider.

If you are experiencing severe or urgent symptoms, seek immediate medical attention by calling emergency services or visiting the nearest emergency department.